The Kinetics of Effect of Neuromuscular Blocking Drugs.
نویسندگان
چکیده
منابع مشابه
The kinetics of effect of neuromuscular blocking drugs.
In attempts to derive pharmacokinetic constants from effect data three methods were explored, using non-depolarizing neuromuscular blocking drugs as the paradigm for obtaining effect data. The first method, based on the simple assumption that following two doses, the drug concentrations at times of equal effect during recovery, were equal. Provided that recovery took place in the log-linear dru...
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Neuromuscular blocking drugs are designed to bind to the nicotinic receptor at the neuromuscular junction. However, they also interact with other acetylcholine receptors in the body. Binding to these receptors causes adverse effects that vary with the specificity for the cholinergic receptor in question. Moreover, all neuromuscular blocking drugs may cause hypersensitivity reactions. Often the ...
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ژورنال
عنوان ژورنال: The Keio Journal of Medicine
سال: 1994
ISSN: 1880-1293,0022-9717
DOI: 10.2302/kjm.43.27